General Information

  • ID:  hor001101
  • Uniprot ID:  NA
  • Protein name:  FLRFamide
  • Gene name:  NA
  • Organism:  Meloidogyne incognita
  • Family:  FMRFamide related peptide family
  • Source:  animal
  • Expression:  NA
  • Disease:  NA
  • Comments:  NA
  • Taxonomy:  NA
  • GO MF:  NA
  • GO BP:  NA
  • GO CC:  NA

Sequence Information

  • Sequence:  FLRF
  • Length:  4
  • Propeptide:  NA
  • Signal peptide:  NA
  • Modification:  T4 Phenylalanine amide
  • Glycosylation:  NA
  • Mutagenesis:  NA

Activity

  • Function:  Increased M. incognita body movement frequency 45% at 1 mM but did not affect stylet activity
  • Mechanism:  NA
  • Cross BBB:  NA
  • Target:  NA
  • Target Unid:  NA
  • IC50: NA
  • EC50: NA
  • ED50: NA
  • kd: NA
  • Half life: NA

Structure

  • Disulfide bond:  NA
  • Structure ID:  NA
  • Structure: (PDB_ID-from https://www.rcsb.org/; AlphaFold_DB_ID-from https://alphafold.ebi.ac.uk/; hordbxxxxxx_AF2.pdb was predicted structure by AlphaFold2; hordbxxxxxx_ESM.pdb was predicted structure by ESMFold)
  •    hor001101_AF2.pdbhor001101_ESM.pdb

Physical Information

Mass: 63540 Formula: C30H43N7O5
Absent amino acids: ACDEGHIKMNPQSTVWY Common amino acids: F
pI: 10.55 Basic residues: 1
Polar residues: 0 Hydrophobic residues: 3
Hydrophobicity: 122.5 Boman Index: -404
Half-Life: 1.1 hour Half-Life Yeast: 3 min
Half-Life E.Coli: 2 min Aliphatic Index 97.5
Instability Index: 5565 Extinction Coefficient cystines: 0
Absorbance 280nm: 0

Literature

  • PubMed ID:  18005465
  • Title:  Responses of Heterodera Glycines and Meloidogyne Incognita to Exogenously Applied Neuromodulators